Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A theoretically-based experimental approach for identifying vascular constitutive relations.

J D Humphrey1, R K Strumpf, F C Yin

  • 1Dept of Mechanical Engineering, University of Maryland, Baltimore 21228.

Biorheology
|January 1, 1989
PubMed
Summary

This study introduces a new method to determine vascular constitutive relations using biomechanical experiments. The approach accounts for complex factors like large deformations and material heterogeneity in blood vessels.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Arterial Growth and Remodeling in Layered and Toroidal Geometries Using Constrained Mixture Theory.

International journal for numerical methods in biomedical engineering·2026
Same author

Controlled intramural fluid injection to quantify propensity to thoracic aortic dissection.

bioRxiv : the preprint server for biology·2026
Same author

Transcriptional regulation of postnatal aortic development.

Cells & development·2024
Same author

Central Artery Hemodynamics in Angiotensin II-Induced Hypertension and Effects of Anesthesia.

Annals of biomedical engineering·2024
Same author

New computational approach to shunt design in congenital heart palliation.

Journal of biomechanics·2023
Same author

Ex vivo biomechanical characterization of umbilical vessels: Possible shunts in congenital heart palliation.

Journal of biomechanics·2023

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Computational Mechanics

Background:

  • Understanding vascular tissue mechanics is crucial for diagnosing and treating cardiovascular diseases.
  • Existing models for vascular constitutive relations often oversimplify complex biomechanical behaviors.
  • Accurate constitutive models are needed to predict vascular response under physiological loads.

Purpose of the Study:

  • To develop a generalizable framework for identifying vascular constitutive relations directly from experimental data.
  • To propose a methodology that accounts for large deformations, nonlinear material behavior, load-dependent anisotropy, material heterogeneity, and incompressibility.
  • To illustrate the application of this framework to elastic arteries, considering the distinct behaviors of the media and adventitia.

Related Experiment Videos

Main Methods:

  • Employing a structurally-motivated phenomenological formulation.
  • Integrating data-driven approaches to determine material properties.
  • Analyzing biomechanical experiments designed to capture complex tissue responses.
  • Separately modeling the mechanical behavior of arterial layers (media and adventitia).

Main Results:

  • A robust methodology for directly identifying vascular constitutive relations from experimental data.
  • The framework successfully incorporates key biomechanical complexities of vascular tissue.
  • Demonstrated application to elastic arteries, providing insights into layered tissue behavior.

Conclusions:

  • The proposed approach offers a powerful tool for characterizing vascular biomechanics.
  • This data-driven, structurally-informed method provides advantages over traditional formulations.
  • The framework is broadly applicable to various vessels and airways, advancing the field of vascular mechanics.