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Maternal xylitol and mutans streptococci transmission
1Kent Community Health Foundation Trust, Faversham Kent.
Evidence-Based Dentistry
|June 27, 2015
Summary
Maternal xylitol gum use significantly reduced Mutans Streptococci (MS) transmission to infants. This intervention shows promise in preventing early childhood cavities by lowering MS levels.
Area of Science:
- Oral microbiology and pediatric dentistry.
- Evidence-based dentistry and systematic reviews.
Background:
- Mutans Streptococci (MS) are a primary cause of early childhood caries.
- Mother-to-child transmission of MS is a significant factor in infant oral health.
- Preventive strategies targeting maternal oral bacteria are crucial for infant dental health.
Purpose of the Study:
- To evaluate the efficacy of maternal xylitol gum consumption in reducing Mutans Streptococci (MS) colonization in infants.
- To assess the impact of maternal xylitol use on the mother-to-child transmission of MS.
Main Methods:
- Systematic review and meta-analysis of randomized or quasi-randomized controlled trials.
- Searched multiple databases (PubMed, EMBASE, SCOPUS, Cochrane) and ClinicalTrials.gov.
- Assessed risk of bias and methodological quality of included studies.
Main Results:
- Eleven studies involving 601 patients were analyzed.
- Maternal xylitol gum use was associated with a significant reduction in MS in infants.
- Risk ratios indicated a protective effect against MS transmission at various time points.
Conclusions:
- Maternal xylitol consumption effectively reduces mother-to-child transmission of salivary MS.
- This intervention shows potential for preventing early childhood caries.
- Findings suggest the need for further research to address potential biases.
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