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(18)F-FDG PET/MRI for therapy response assessment in sarcoma: comparison of PET and MR imaging results
Markus Kajo Schuler1, Ivan Platzek2, Bettina Beuthien-Baumann3
1Department of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Fetscherstraße 74, 01307, Dresden.
Background:
(18)F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) has proven to be of substantial benefit in imaging of sarcoma patients. We therefore investigated the feasibility and benefit of combined PET/magnetic resonance imaging (MRI).
Methods:
Twelve patients with sarcoma who underwent FDG PET/MRI for staging and response assessment after chemotherapy were included.
Results:
Based on contrast-enhanced MRI and application of Choi criteria, therapy response was classified as stable disease in 6/12 patients (50%) and as partial remission in 6/12 patients (50%).
Conclusion:
In sarcoma patients, response assessment using Choi criteria based on contrast-enhanced MRI in comparison to FDG PET imaging only demonstrates slight correlation.
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