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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Updated: Apr 8, 2026

Iris Fixation via External Pentagram Suturing
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Primary angle-closure glaucoma: an update.

Carrie Wright1, Mohammed A Tawfik1, Michael Waisbourd1

  • 1Wills Eye Hospital, Philadelphia, PA, USA.

Acta Ophthalmologica
|June 30, 2015
PubMed
Summary
This summary is machine-generated.

Primary angle-closure glaucoma, a leading cause of blindness, involves iris and trabecular meshwork contact. Effective treatments include medications, laser procedures, and surgery to manage intraocular pressure and prevent vision loss.

Keywords:
angle-closure glaucomaargon laser iridoplastylensectomyperipheral iridotomyphacoemulsificationplateau irisprimary angle closurepupillary blockreview

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Area of Science:

  • Ophthalmology
  • Glaucoma Research

Background:

  • Primary angle-closure glaucoma (PACG) is a significant cause of blindness globally.
  • It is characterized by iris contact with the trabecular meshwork, often in eyes with specific anatomical features.
  • PACG disproportionately affects women, the elderly, hyperopic individuals, and populations in Asia.

Purpose of the Study:

  • To review the diagnosis and management of primary angle-closure glaucoma.
  • To highlight current and emerging treatment strategies for this condition.

Main Methods:

  • Diagnosis involves gonioscopy, potentially augmented by anterior segment optical coherence tomography and ultrasound biomicroscopy.
  • Treatment focuses on lowering intraocular pressure and monitoring glaucoma progression.
  • Therapeutic interventions include medical management, laser treatments (peripheral iridotomy, laser iridoplasty), and surgical options (phacoemulsification, endoscopic cyclophotocoagulation, trabeculectomy).

Main Results:

  • Various medical, laser, and surgical treatments are available to control intraocular pressure and manage angle closure.
  • Phacoemulsification is a viable option for both cataractous and clear lenses.
  • Trabeculectomy remains effective for advanced cases.

Conclusions:

  • Effective management of primary angle-closure glaucoma requires a multi-faceted approach tailored to individual patient needs.
  • Ongoing research aims to further elucidate genetic factors and long-term treatment efficacy.
  • Timely diagnosis and intervention are crucial to prevent vision loss from PACG.