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Updated: Apr 8, 2026

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Repeated Orotracheal Intubation in Mice
Published on: March 27, 2020
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[Study on correlation between otitis media with effusion and tracheal intubation]
Summary
Long-term tracheal intubation increases the risk of otitis media with effusion (OME). Factors like ventilator use, nasotracheal tubes, and conscious disturbance are linked to OME, while glucocorticoids may reduce its incidence.
Area of Science:
- Otolaryngology
- Critical Care Medicine
- Pediatrics
Background:
- Otitis media with effusion (OME) is a common condition, particularly in children.
- Long-term tracheal intubation is a medical intervention used in critically ill patients.
- Understanding factors contributing to OME in intubated patients is crucial for patient care.
Purpose of the Study:
- To investigate the risk factors associated with the development of otitis media with effusion (OME) in patients requiring prolonged endotracheal intubation.
- To identify specific clinical parameters and interventions that correlate with OME occurrence in this patient population.
Main Methods:
- A retrospective study comparing 47 patients with endotracheal intubation exceeding 7 days to 20 control patients.
- Analysis of relationships between OME and variables including age, gender, intubation method, duration, breathing patterns, consciousness, and gastric tube position.
Main Results:
- OME was diagnosed in 27 of 47 (57.4%) patients with long-term intubation, compared to none in the control group.
- Significant associations found between OME and ventilator use in PEEP mode, nasotracheal intubation, conscious disturbance, and intubation duration over 10 days.
- Higher OME rates were observed in patients with nasal compared to oral intake, and glucocorticoid use was linked to a decreased OME incidence.
Conclusions:
- Prolonged tracheal intubation (over 7 days) is associated with an increased incidence of OME.
- Specific factors such as PEEP ventilation, nasotracheal tubes, and altered consciousness are strongly linked to OME development.
- Glucocorticoid administration appears to mitigate the risk of OME in intubated patients.
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