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Cognitive function in chronic rhinosinusitis: a controlled clinical study.

Zachary M Soler1, Mark A Eckert1, Kristina Storck1

  • 1Division of Rhinology and Sinus Surgery, Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, SC.

International Forum of Allergy & Rhinology
|July 1, 2015
PubMed
Summary
This summary is machine-generated.

Patients with chronic rhinosinusitis (CRS) experience significant cognitive dysfunction and fatigue. Objective testing revealed slower reaction times in CRS patients compared to controls, highlighting a need for further investigation into treatment impacts.

Keywords:
attentionchronic rhinosinusitiscognitioncognitive functionfatiguememory

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Area of Science:

  • Neuroscience
  • Otolaryngology
  • Cognitive Psychology

Background:

  • Cognitive dysfunction in chronic rhinosinusitis (CRS) is understudied.
  • Previous cognitive assessments in CRS often lack objective measures and controls.
  • This study addresses the need for comprehensive cognitive evaluation in CRS patients.

Purpose of the Study:

  • To characterize cognitive function deficits in CRS patients.
  • To compare subjective and objective cognitive measures between CRS patients and controls.
  • To investigate the impact of CRS on cognitive performance.

Main Methods:

  • Recruited 50 CRS patients and 50 non-CRS controls.
  • Assessed subjective cognition using the Cognitive Failures Questionnaire (CFQ) and Fatigue Severity Scale (FSS).
  • Measured objective cognitive function with the Automated Neuropsychological Assessment Metrics (ANAM) battery.

Main Results:

  • CRS patients reported significantly higher cognitive failures (CFQ) and fatigue (FSS) than controls.
  • Objective testing showed slower simple reaction times in CRS patients.
  • These differences remained significant after controlling for confounding factors.

Conclusions:

  • Patients with CRS exhibit significant subjective and objective cognitive impairments, including fatigue and slower reaction times.
  • Further research is needed to explore the effects of CRS treatments on cognitive function.
  • Cognitive dysfunction should be considered in the comprehensive management of CRS.