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Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry
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Gene delivery polymer structure-function relationships elucidated via principal component analysis

C J Bishop1, B Abubaker-Sharif, T Guiriba

  • 1The Johns Hopkins University School of Medicine, Department of Biomedical Engineering, Translational Tissue Engineering Center, 400 North Broadway, Baltimore MD, USA. green@jhu.edu.

Chemical Communications (Cambridge, England)
|July 2, 2015
PubMed
Summary

Researchers used principal component analysis to understand how chemical properties of poly(beta-amino ester)s impact their effectiveness in non-viral gene delivery and cell interactions.

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