Stress echocardiography in paediatric cardiology
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Updated: Apr 8, 2026

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
Published on: January 27, 2023
Barbara Cifra1, Andreea Dragulescu1, William L Border2
1Division of Cardiology, Department of Pediatrics, The Labatt Family Heart Centre, The Hospital for Sick Children, The University of Toronto, 555 University Avenue, Toronto, ON, Canada M5G 1X8.
Insights
Stress echocardiography assesses heart function in adults and children, aiding in diagnosing coronary artery disease (CAD) and valve issues. Advanced techniques improve evaluation of congenital heart disease and chemotherapy effects.
Area of Science:
- Cardiology
- Echocardiography
- Pediatric Cardiology
Background:
- Stress echocardiography is a key diagnostic tool in adult cardiology for evaluating coronary artery disease (CAD) and valvular heart disease.
- In pediatrics, it's crucial for detecting ischemia in conditions like post-transplant, Kawasaki Disease, and anomalous coronary arteries.
- It also assesses hemodynamic responses in congenital heart disease and detects early myocardial dysfunction.
Purpose of the Study:
- To provide an overview of the current applications of stress echocardiography in both adult and pediatric cardiology.
- To highlight the evolution of stress echocardiography techniques and their integration with advanced imaging modalities.
- To emphasize its role in managing complex cardiac conditions and specific patient populations.
Main Methods:
- Utilizes exercise or pharmacologic (dobutamine) stress to provoke cardiac responses.
- Employs advanced imaging like tissue Doppler and strain technology for quantitative functional analysis.
- Reviews established and emerging clinical applications across diverse patient groups.
Main Results:
- Stress echocardiography effectively detects myocardial ischemia and assesses the hemodynamic significance of valve disease.
- Exercise stress echocardiography is increasingly preferred over dobutamine stress echocardiography in older children.
- Integrated imaging technologies enhance the quantitative assessment of systolic and diastolic function.
Conclusions:
- Stress echocardiography remains a vital, versatile imaging modality in cardiology for adults and children.
- Its applications extend from diagnosing coronary artery disease to managing complex congenital and acquired heart conditions.
- Technological advancements continue to refine its diagnostic accuracy and clinical utility.
Abstract:
Stress echocardiography is a well-established technique in adult cardiology and is mainly used for assessing regional myocardial function in patients with known or suspected coronary artery disease (CAD). Apart from detecting ischaemia, stress echocardiography has found its place in the assessment of the haemodynamic significance of valve disease, particularly in selected patients with aortic stenosis and mitral regurgitation. Also in the paediatric population, stress imaging is most commonly used for the detection of ischaemia in patients with CADs such as post heart transplantation, Kawasaki Disease, and abnormal origin of coronary arteries. Other paediatric indications include the haemodynamic and myocardial response in patients with different types of congenital heart disease, the early detection of myocardial dysfunction in specific populations such as patients after anthracycline exposure, and the evaluation of pulmonary artery pressures and the right ventricular functional response. Techniques have evolved over time and in different paediatric echocardiographic laboratories, exercise stress echocardiography is replacing dobutamine stress echocardiography in older children. Moreover, integrating tissue Doppler and strain technology with stress imaging allows a more quantitative analysis of regional and global systolic and diastolic function. Current clinical applications mainly include patients after transplant, suspected CAD, and hypertrophic cardiomyopathy.
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