Related Experiment Video

Updated: Apr 7, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

88.5K

[An infant with a bowed lower leg]

Inge J S M L Vanhooymissen1, Rody Ouwendijk, Pauline M Snijder

  • 1Erasmus MC, Rotterdam.

Nederlands Tijdschrift Voor Geneeskunde
|July 2, 2015
PubMed

Insights

A 5-month-old boy with leg bowing was diagnosed with neurofibromatosis type 1. This genetic condition was confirmed due to his mother also having neurofibromatosis.

Area of Science:

  • Pediatric Orthopedics
  • Clinical Genetics

Background:

  • Neurofibromatosis type 1 (NF1) is a genetic disorder.
  • NF1 can manifest with skeletal abnormalities, including tibial bowing.

Observation:

  • A 5-month-old boy presented with anterolateral bowing of the left tibia and fibula.
  • Radiographic imaging revealed intramedullary sclerosis in the affected bones.

Findings:

  • The radiographic findings were characteristic of neurofibromatosis type 1.
  • The boy's mother had a confirmed diagnosis of neurofibromatosis, supporting the genetic link.

Implications:

  • Early diagnosis of NF1 in infants is crucial for timely management.
  • Genetic counseling and regular monitoring are essential for affected children.

More Related Videos

Quantifying Learning in Young Infants: Tracking Leg Actions During a Discovery-learning Task11:18

Quantifying Learning in Young Infants: Tracking Leg Actions During a Discovery-learning Task

Published on: June 1, 2015

11.2K
Manual Muscle Testing: A Method of Measuring Extremity Muscle Strength Applied to Critically Ill Patients09:44

Manual Muscle Testing: A Method of Measuring Extremity Muscle Strength Applied to Critically Ill Patients

Published on: April 12, 2011

83.8K

Related Concept Videos

Bones of the Lower Limb: Femur and Patella01:16

Bones of the Lower Limb: Femur and Patella

The femur is the body's longest and strongest bone spanning the thigh region. Its head articulates with the acetabulum of the hip bone to form the hip joint. A minor indentation on the medial side of the femoral head, called the fovea capitis, serves as the site of attachment for the ligament of the head of the femur. This weak ligament spans the femur and acetabulum and supports the hip joint. The narrowed region below the head is the neck of the femur. The inclination angle between the...
9.3K
Assessing Blood pressure in the Leg01:11

Assessing Blood pressure in the Leg

Proper measurement of leg blood pressure is a critical skill for healthcare providers, ensuring precise and reliable readings. When performed correctly, this procedure informs patient care and enhances the efficacy of interventions. The following text outlines step-by-step guidelines to measure blood pressure in the leg, providing clarity and ease of understanding for practitioners.
Preparation:
15.5K
Bones of the Lower Limb: Tibia and Fibula01:10

Bones of the Lower Limb: Tibia and Fibula

The tibia is the main weight-bearing bone of the lower leg. It is larger than the fibula with which it is paired. The tibia is also the second longest bone in the body and is located right below the skin. The proximal end of the tibia forms the medial and the lateral condyle, which articulates with the condyles of the femur to form the knee joint. Between the articulating surfaces is the irregular elevated area known as the intercondylar eminence that serves as the inferior attachment point for...
15.0K
Muscles that Move the Leg01:23

Muscles that Move the Leg

The movement of the legs is facilitated by numerous muscles located within the anterior, medial, and posterior compartments of the thigh.
Anterior Compartment
The quadriceps femoris, the most visible muscle of the anterior compartment, is integral for leg extension and thigh flexion. It is formed by merging four distinct muscles — the vastus lateralis, vastus medialis, vastus intermedius, and rectus femoris. The quadriceps tendon, a shared tendon of the four quadriceps muscles, is affixed...
6.4K
Veins of Lower Limbs01:15

Veins of Lower Limbs

The human body consists of an intricate network of veins responsible for the crucial task of blood drainage from the lower limbs. These veins can be categorized into two main types: deep veins and superficial veins.
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the...
3.1K
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
4.0K