Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Metabolic States of the Body: The Postabsorptive State01:18

Metabolic States of the Body: The Postabsorptive State

1.6K
The postabsorptive state usually starts about four hours after a meal and lasts until the next meal is eaten. During this time, the digestive system stops absorbing nutrients, and the body uses stored energy reserves to maintain stable blood glucose levels.
Initially, glycogen stored in the liver is broken down to release glucose into the bloodstream, while glycogen in the muscles is broken down to supply glucose for energy directly within the muscle cells. As glycogen stores diminish,...
1.6K
Metabolic States of the Body: The Absorptive State01:25

Metabolic States of the Body: The Absorptive State

2.1K
During the absorptive state, which lasts approximately four hours after a meal, the body absorbs nutrients from the gastrointestinal tract. The carbohydrates, proteins, and lipids we consume are broken down into monosaccharides, amino acids, and free fatty acids for absorption. While carbohydrates and proteins are absorbed as-is, lipids are absorbed in their broken-down forms and then re-esterified into triglycerides within enterocytes before being packaged into chylomicrons. These absorbed...
2.1K
What is Metabolism?00:52

What is Metabolism?

136.6K
Overview
136.6K
Metabolic Rate01:25

Metabolic Rate

1.4K
The human body is a powerhouse of energy, with every cell performing numerous functions that require energy. This energy production and consumption is measured by the metabolic rate, which quantifies the total heat generated by all the body's chemical reactions and mechanical work. This measurement helps to determine the rate of kilocalorie (kcal) consumption needed to fuel all ongoing activities.
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence...
1.4K
Overview of Metabolism01:40

Overview of Metabolism

41.2K
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
41.2K
Regulation of Metabolism01:19

Regulation of Metabolism

12.4K
Cellular needs and conditions vary from cell to cell and change within individual cells over time. For example, the required enzymes and energetic demands of stomach cells are different from those of fat storage cells, skin cells, blood cells, and nerve cells. Furthermore, a digestive cell works much harder to process and break down nutrients during the time that closely follows a meal compared with many hours after a meal. As these cellular demands and conditions vary, so do the amounts and...
12.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Targeting Cellular Senescence Enhances Post-Burn Wound Healing in Aged Mice.

Shock (Augusta, Ga.)·2026
Same author

Shock Synopsis December 2025.

Shock (Augusta, Ga.)·2026
Same author

Shock Synopsis March 2026.

Shock (Augusta, Ga.)·2026
Same author

High-Dose Intravenous Vitamin C and Mortality and Organ Dysfunction in Severe Burn Injury: The VICTORY Randomized Clinical Trial.

JAMA·2026
Same author

Shock Synopsis June 2026.

Shock (Augusta, Ga.)·2026
Same author

Therapeutic implications of epigenetic alterations in burns: a new frontier in burn medicine.

Clinical science (London, England : 1979)·2026
Same journal

Ultra-Early Mobilization After Split-Thickness Skin Grafting in Burn Patients Is Not Associated with Graft Loss.

Journal of burn care & research : official publication of the American Burn Association·2026
Same journal

Classification Systems & Clinical Outcomes of Axillary Burn Contracture: A Systematic Review & Meta Analysis.

Journal of burn care & research : official publication of the American Burn Association·2026
Same journal

Synthesis of Protocols for Frostbite Care from the FROST Study Sites.

Journal of burn care & research : official publication of the American Burn Association·2026
Same journal

Identifying Risk Factors for Readmission amongst Unhoused Burn Patients.

Journal of burn care & research : official publication of the American Burn Association·2026
Same journal

Family Income and Recovery Outcomes in Pediatric Burn Survivors: A Burn Model System National Database Study Assessing Functional and Psychosocial Differences.

Journal of burn care & research : official publication of the American Burn Association·2026
Same journal

LIBRE GO!: A Mobile Application for Longitudinal Social Participation Assessment and Resources Connection after Burn Injury.

Journal of burn care & research : official publication of the American Burn Association·2026
See all related articles

Related Experiment Video

Updated: Apr 7, 2026

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging
11:43

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging

Published on: December 30, 2016

11.2K

Postburn Hypermetabolism: Past, Present, and Future.

Marc G Jeschke1

  • 1From the *Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; †Division of Plastic Surgery, Department of Surgery, and Department of Immunology, University of Toronto, Toronto, Ontario, Canada.

Journal of Burn Care & Research : Official Publication of the American Burn Association
|July 2, 2015
PubMed
Summary
This summary is machine-generated.

Severe burn injuries trigger hypermetabolism, a complex response not fully understood. This review explores its history, current knowledge, and new treatments to improve patient outcomes.

More Related Videos

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans
04:54

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans

Published on: June 2, 2023

2.2K
Author Spotlight: Illuminating New Avenues for Adipose Tissue Metabolism and Disease Prevention
02:55

Author Spotlight: Illuminating New Avenues for Adipose Tissue Metabolism and Disease Prevention

Published on: October 6, 2023

2.2K

Related Experiment Videos

Last Updated: Apr 7, 2026

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging
11:43

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging

Published on: December 30, 2016

11.2K
Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans
04:54

Using a Combination of Indirect Calorimetry, Infrared Thermography, and Blood Glucose Levels to Measure Brown Adipose Tissue Thermogenesis in Humans

Published on: June 2, 2023

2.2K
Author Spotlight: Illuminating New Avenues for Adipose Tissue Metabolism and Disease Prevention
02:55

Author Spotlight: Illuminating New Avenues for Adipose Tissue Metabolism and Disease Prevention

Published on: October 6, 2023

2.2K

Area of Science:

  • Burn injury research
  • Metabolic response
  • Trauma and critical care

Background:

  • Hypermetabolism is a universal physiological response to severe burn injury.
  • Despite extensive research over a century, the complete mechanisms of postburn hypermetabolism remain elusive.
  • Understanding this complex metabolic state is crucial for effective patient management.

Purpose of the Study:

  • To provide a comprehensive overview of the historical understanding of postburn hypermetabolism.
  • To present novel insights into the pathophysiology of this metabolic response.
  • To delineate current and emerging treatment strategies aimed at modulating hypermetabolism and improving outcomes for burn patients.

Main Methods:

  • Literature review of historical and contemporary research on burn hypermetabolism.
  • Synthesis of current understanding of the components and drivers of the hypermetabolic state.
  • Analysis of therapeutic interventions targeting metabolic modulation in burn care.

Main Results:

  • The review details the evolution of understanding hypermetabolism from the 19th century to the present.
  • Novel insights into the intricate pathways contributing to the hypermetabolic state are discussed.
  • Various treatment options, including nutritional support and pharmacological interventions, are presented.

Conclusions:

  • Postburn hypermetabolism is a critical factor influencing patient recovery and outcomes.
  • Continued research is essential to fully elucidate the mechanisms and develop targeted therapies.
  • Modulating hypermetabolism holds significant promise for improving the survival and quality of life for severe burn patients.