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Update and Review: Maternal Serum Screening
1Department of Pediatrics, University of Vermont College of Medicine, Burlington, Vermont.
Journal of Genetic Counseling
|July 5, 2015
Abstract:
Maternal serum levels of alpha fetoprotein (AFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3) can be used to screen pregnancies for neural tube defects, Down syndrome, Trisomy 18, and pregnancy complications. This article summarizes the most recent information regarding maternal serum screening, including genetic counseling issues.

