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Fluorophore ATCUN complexes: combining agent and probe for oxidative DNA cleavage
1Institut für Chemie und Biochemie, Freie Universität Berlin, Fabeckstr. 34/36, 14195 Berlin, Germany. nora.kulak@fu-berlin.de.
Chemical Communications (Cambridge, England)
|July 7, 2015
Abstract:
DNA can be oxidatively cleaved by copper complexes of the ATCUN peptide (amino terminal Cu(II)- and Ni(II)-binding motif). In order to investigate the fate of the metal ion throughout this process, we have exploited quenching/dequenching effects of conjugated fluorophores.
