Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Applications Of NMR In Biology

Applications Of NMR In Biology

Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Light-guiding capillaries: a robust optofluidic platform for nanoparticle tracking analysis.

Lab on a chip·2026

Same author

A secondary upstream invasion of round goby in the Great Lakes Basin over fourteen years following a dam removal.

Journal of environmental management·2026

Same author

Effect of hybrid field coupling in nanostructured surfaces on anisotropic signal detection in nanoscale infrared spectroscopic imaging methods.

Faraday discussions·2026

Same author

Comparison of glucose concentrations in simultaneously collected plasma and serum samples from outpatients in a routine laboratory setting.

PloS one·2026

Same author

Estimation of Sex- and Age-Specific Reference Values for Serum Creatinine Using Three Indirect Methods in a Multicenter Setting.

The journal of applied laboratory medicine·2026

Same author

Digital Transformation and Artificial Intelligence in Radiology: Challenges and Opportunities for Clinical Practice, Research, and the Next Generation.

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin·2025

Search research articles

Related Experiment Video

Updated: Apr 7, 2026

Biofunctionalization of Magnetic Nanomaterials

Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

Magnetic nanoparticles adapted for specific biomedical applications.

Silvio Dutz, Robert Müller, Dietmar Eberbeck

Biomedizinische Technik. Biomedical Engineering

|July 7, 2015

Summary

Researchers optimized magnetic nanoparticles (MNPs) for biomedical uses by controlling their structure and size. Novel magnetic multicore nanoparticles show promise for hyperthermia cancer treatment, reaching therapeutic temperatures rapidly in vivo.

More Related Videos

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Published on: August 22, 2014

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

Related Experiment Videos

Last Updated: Apr 7, 2026

Biofunctionalization of Magnetic Nanomaterials

Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Published on: August 22, 2014

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

Area of Science:

Materials Science
Nanotechnology
Biomedical Engineering

Background:

Magnetic nanoparticles (MNPs) are versatile tools in biomedical applications.
Specific applications necessitate tailored MNP properties, including crystal structure, size, and distribution.
Optimization of MNPs is crucial for enhancing their efficacy in various biomedical fields.

Purpose of the Study:

To develop improved aqueous precipitation procedures for synthesizing magnetic iron oxide nanoparticles.
To investigate novel magnetic multicore nanoparticles for enhanced biomedical applications, particularly hyperthermia.
To demonstrate the tunability of MNP magnetic properties through structural and size modifications.

Main Methods:

Developed two novel aqueous precipitation procedures for magnetic iron oxide nanoparticle synthesis.
Focused on cyclic growth to control MNP core formation and size.
Synthesized magnetic multicore nanoparticles composed of ~10 nm cores in 40-80 nm clusters.

Main Results:

Achieved controlled MNP synthesis with tunable properties via optimized precipitation.
Magnetic multicore nanoparticles demonstrated high potential for hyperthermia applications.
In vivo experiments showed rapid heating to therapeutic temperatures (1% concentration, H=24 kA/m, f=410 kHz).

Conclusions:

Tuning magnetic properties of MNPs is achievable by altering their structure, size, and size distribution.
Controlled particle size during synthesis or size-dependent fractionation enables property optimization.
The developed magnetic nanoparticles exhibit significant potential for diverse biomedical applications.