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Correlation between Plasma Level of Monocyte Chemotactic Protein 1 and Acute Aortic Dissection
Fan-Yan Luo1, Zi-Hou Liu1, Hai-He Jiang1
1Department of Cardiothoracic Surgery,Xiangya Hospital,Central South University,Changsha 410008,China.
Objective:
To investigate the potential association between monocyte chemotactic protein 1(MCP-1)in plasma and acute aortic dissection(AAD).
Methods:
A total of 110 patients with Stanford type A AAD who had received emergent surgical treatment in Xiangya hospital from September 2011 to September 2014 were enrolled in as the study group;meanwhile,110 patients with simple hypertension who had received treatment in department of cardiology were chosen as the control group. The plasma level of MCP-1 was measured and then compared between these two groups.
Results:
The plasma level of MCP-1 in the study group was(257.79±86.52)pg/ml,which was significantly higher than that in control group [(136.57±48.84)pg/ml](P<0.001).
Conclusion:
There may be a correlation between plasma MCP-1 level and AAD.
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