Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vaccine Production01:23

Vaccine Production

72
Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
72
Cancer Vaccines01:30

Cancer Vaccines

1.3K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Virus-like Particles Carrying a Porcine Circovirus Type 2b Peptide Induce an Antibody Response and Reduce Viral Load in Immunized Pigs.

Vaccines·2026
Same author

The rpZDIII vaccine triggers vertical protection on newborn mice against zika virus infection.

Vaccine·2025
Same author

The expression of <i>arsC, ɣ-ecs, and acr3</i> in <i>Chlamydomonas reinhardtii</i> resulted in an enhanced arsenic removal efficiency compared to a wild-type strain.

International journal of phytoremediation·2025
Same author

Microalgae-made biopharmaceuticals and their potential role in the One Health approach.

Trends in biotechnology·2025
Same author

Covalent Functionalization of Layered Double Hydroxides to Generate Peptide-Based SARS-CoV-2 Nanovaccine.

Materials (Basel, Switzerland)·2025
Same author

Establishment of a Carrot Cell Plant Growth Regulators-free System to Produce a Low-Cost Vaccine Candidate.

Planta medica·2025

Related Experiment Video

Updated: Apr 7, 2026

Whole-animal Imaging and Flow Cytometric Techniques for Analysis of Antigen-specific CD8+ T Cell Responses after Nanoparticle Vaccination
11:07

Whole-animal Imaging and Flow Cytometric Techniques for Analysis of Antigen-specific CD8+ T Cell Responses after Nanoparticle Vaccination

Published on: April 29, 2015

13.8K

Gold nanoparticles and vaccine development.

Jorge Alberto Salazar-González1, Omar González-Ortega, Sergio Rosales-Mendoza

  • 1Laboratorio de Biofarmacéuticos Recombinantes, Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, Av. Dr. Manuel Nava 6, SLP, 78210, México.

Expert Review of Vaccines
|July 9, 2015
PubMed
Summary

Gold nanoparticles (AuNPs) offer a promising platform for developing advanced mucosal vaccines. This review summarizes AuNP synthesis and highlights their potential in creating effective vaccines against widespread diseases.

Keywords:
antigen uptakedelivery vehiclefunctionalizationimmunogenicityintranasal immunizationmucosal vaccinenanoparticlesoral immunizationtoxicityvaccine cost

More Related Videos

Production of E. coli-expressed Self-Assembling Protein Nanoparticles for Vaccines Requiring Trimeric Epitope Presentation
10:58

Production of E. coli-expressed Self-Assembling Protein Nanoparticles for Vaccines Requiring Trimeric Epitope Presentation

Published on: August 21, 2019

8.1K
Preparation, Characteristics, Toxicity, and Efficacy Evaluation of the Nasal Self-Assembled Nanoemulsion Tumor Vaccine In Vitro and In Vivo
07:33

Preparation, Characteristics, Toxicity, and Efficacy Evaluation of the Nasal Self-Assembled Nanoemulsion Tumor Vaccine In Vitro and In Vivo

Published on: September 28, 2022

2.4K

Related Experiment Videos

Last Updated: Apr 7, 2026

Whole-animal Imaging and Flow Cytometric Techniques for Analysis of Antigen-specific CD8+ T Cell Responses after Nanoparticle Vaccination
11:07

Whole-animal Imaging and Flow Cytometric Techniques for Analysis of Antigen-specific CD8+ T Cell Responses after Nanoparticle Vaccination

Published on: April 29, 2015

13.8K
Production of E. coli-expressed Self-Assembling Protein Nanoparticles for Vaccines Requiring Trimeric Epitope Presentation
10:58

Production of E. coli-expressed Self-Assembling Protein Nanoparticles for Vaccines Requiring Trimeric Epitope Presentation

Published on: August 21, 2019

8.1K
Preparation, Characteristics, Toxicity, and Efficacy Evaluation of the Nasal Self-Assembled Nanoemulsion Tumor Vaccine In Vitro and In Vivo
07:33

Preparation, Characteristics, Toxicity, and Efficacy Evaluation of the Nasal Self-Assembled Nanoemulsion Tumor Vaccine In Vitro and In Vivo

Published on: September 28, 2022

2.4K

Area of Science:

  • Vaccinology and Nanotechnology
  • Biocompatible Materials in Drug Delivery

Background:

  • Mucosal vaccines are crucial for broad immunization but require enhancement.
  • Gold nanoparticles (AuNPs) are biocompatible and antigen-functionalizable, making them suitable vaccine carriers.
  • Research in AuNPs for vaccinology has advanced significantly.

Purpose of the Study:

  • To review gold nanoparticle synthesis methodologies.
  • To provide an overview of current AuNP-based vaccine development.
  • To discuss the implications for mucosal vaccine advancement.

Main Methods:

  • Literature review of AuNP synthesis techniques.
  • Survey of ongoing research in AuNP-based vaccine development.
  • Analysis of AuNPs' role in mucosal vaccine strategies.

Main Results:

  • Summary of various AuNP synthesis approaches.
  • Identification of key AuNP-based vaccines in development.
  • Discussion of AuNP efficacy and potential in mucosal delivery.

Conclusions:

  • Gold nanoparticles show significant potential for next-generation mucosal vaccines.
  • Further research into AuNP synthesis and application is warranted.
  • AuNPs could revolutionize vaccine delivery for widespread diseases.