Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

4.0K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
4.0K
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

473
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
473

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Depth of neutrophil mobilization stratifies survival in ST-elevation myocardial infarction.

Nature cardiovascular research·2026
Same author

Stroke Severity and Functional Benefit of Thrombectomy in Acute M2 Middle Cerebral Artery Occlusion: A Multicenter Cohort Study.

Neurology·2026
Same author

Ischemic Lesion Net Water Uptake Outperforms ASPECTS and CBF Less Than 30% in Predicting Futile Recanalization after Mechanical Thrombectomy.

Radiology·2026
Same author

Endovascular treatment for medium or distal vessel occlusion stroke (DISTAL): 12-month outcomes of a multicentre, open-label, randomised trial.

The Lancet. Neurology·2026
Same author

CD177 Expression on Neutrophils Predicts Ischemic Stroke Outcome in Humans.

Stroke·2026
Same author

How We Can Optimize Dysmenorrhea Treatment: Real-World Results from a Cross-Sectional, Multi-Center Study.

Geburtshilfe und Frauenheilkunde·2026

Related Experiment Video

Updated: Apr 7, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.8K

Explaining the Decrease of In-Hospital Mortality from Ischemic Stroke.

Jens Minnerup1, Heike Wersching2, Michael Unrath2

  • 1Department of Neurology, University of Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.

Plos One
|July 9, 2015
PubMed
Summary

In-hospital mortality for ischemic stroke significantly decreased from 2000 to 2008, driven by improved treatments like early antiplatelet therapy and physiotherapy. These interventions played a key role in reducing stroke patient deaths.

More Related Videos

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
05:41

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

4.7K
Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide
09:52

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Published on: January 15, 2017

18.1K

Related Experiment Videos

Last Updated: Apr 7, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.8K
Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
05:41

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

4.7K
Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide
09:52

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Published on: January 15, 2017

18.1K

Area of Science:

  • Neurology
  • Clinical Medicine
  • Public Health

Background:

  • Ischemic stroke mortality has declined, but the underlying reasons remain unclear.
  • This study investigates trends in in-hospital mortality and associated factors.

Purpose of the Study:

  • To evaluate trends in in-hospital mortality for ischemic stroke patients.
  • To identify factors contributing to observed changes in mortality rates.

Main Methods:

  • Prospective database analysis of 73,614 ischemic stroke patients from 26 hospitals (2000-2011).
  • Assessment of time trends in crude and risk-adjusted in-hospital mortality.
  • Multivariable logistic regression to identify independent predictors of mortality.

Main Results:

  • Observed in-hospital mortality decreased from 6.6% (2000) to 4.6% (2008), then stabilized.
  • Risk-adjusted mortality declined from 2.85% (2000) to 1.86% (2008), with a subsequent increase to 2.32% (2011).
  • Increased use of in-hospital treatments (antiplatelets, antihypertensives, statins, physiotherapy) correlated with decreased mortality.

Conclusions:

  • In-hospital mortality for ischemic stroke reduced by approximately one-third between 2000 and 2008.
  • Improvements in in-hospital management, particularly early antiplatelet therapy and physiotherapy, partially mediated this decline.