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Signet Ring Dermatofibroma, a Rare and Confusing Variant.

Asmaa Gaber Abdou¹, Nancy Youssef Asaad¹

¹Faculty of Medicine, Pathology Department, Menofiya University , Shebein Elkom, Egypt .

Journal of Clinical and Diagnostic Research : JCDR

|July 9, 2015

Summary

Signet ring dermatofibroma is a rare variant of a common skin neoplasm. Careful histopathological examination and immunohistochemistry aid in diagnosing this benign tumor, distinguishing it from malignant conditions.

Keywords:

Benign fibrous histiocytoma CD68 Skin

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Area of Science:

Dermatopathology
Surgical Pathology
Oncology

Background:

Dermatofibroma is a frequent benign fibrohistiocytic tumor of the skin.
Diagnosis is typically straightforward, but rare variants can pose challenges.

Observation:

This report details a signet ring variant of dermatofibroma.
Signet cells in cutaneous neoplasms do not automatically indicate malignancy.

Findings:

The signet ring variant of dermatofibroma presents diagnostic difficulties.
Histopathological examination, including identification of classic areas and immunohistochemistry, is crucial for accurate diagnosis.

Implications:

Recognizing rare variants like signet ring dermatofibroma is important for avoiding misdiagnosis.
This study highlights the utility of detailed histopathological analysis and immunohistochemistry in differentiating benign from potentially malignant cutaneous neoplasms.