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Primary Pancreatic Lymphoma Simulating Acute Cholestatic Hepatitis in a 7-Year-Old Child

Vikrant Sood1, Nitesh Agrawal2, Seema Alam1

  • 1Department of Pediatric Hepatology, Institute of Liver and Biliary Sciences, Vasant Kunj, New Delhi, India.

ACG Case Reports Journal
|July 10, 2015
PubMed

Insights

Primary pancreatic lymphoma in children is rare, especially when it mimics acute hepatitis. This case highlights a diagnostic challenge in pediatric oncology, emphasizing the need for early recognition of unusual presentations.

Area of Science:

  • Pediatric Oncology
  • Hepatology
  • Rare Diseases

Background:

  • Primary pancreatic lymphoma is an uncommon malignancy in pediatric patients.
  • Acute presentation mimicking cholestatic or infective hepatitis is a rare clinical manifestation.

Observation:

  • A 7-year-old child presented with symptoms suggestive of acute infective hepatitis.
  • Initial diagnostic workup focused on infectious etiologies, leading to a delay in considering neoplastic processes.
  • The patient's clinical course and subsequent investigations revealed primary pancreatic lymphoma.

Findings:

  • The case demonstrates a rare presentation of PPL mimicking acute hepatitis.
  • Delayed diagnosis due to atypical presentation complicated the management strategy.
  • Histopathological confirmation was crucial for accurate diagnosis and appropriate treatment initiation.

Implications:

  • This case underscores the importance of considering rare diagnoses in pediatric patients with atypical presentations.
  • Enhanced awareness among clinicians regarding PPL's varied clinical manifestations is necessary.
  • Early recognition and diagnosis of PPL can potentially improve patient outcomes and treatment efficacy.

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