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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Endoscopic Procedures II: Colonoscopy01:25

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The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
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Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
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Drugs for Treatment of Constipation-Predominant IBS01:21

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Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
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Drugs for Treatment of Diarrhea-Predominant IBS01:17

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Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
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Inflammatory Bowel Disease IV: Pharmacological Management01:29

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
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Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
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"Difficult" Colorectal Polyps - Therapeutic Approach.

M Alecu, L Simion, S Ionescu

    Chirurgia (Bucharest, Romania : 1990)
    |July 10, 2015
    PubMed
    Summary
    This summary is machine-generated.

    Endoscopic polypectomy is standard for colorectal polyps, but "difficult" polyps occur in over a third of cases. While mostly manageable endoscopically, some require traditional surgery.

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    Area of Science:

    • Gastroenterology
    • Surgical Oncology
    • Medical Diagnostics

    Background:

    • Endoscopic polypectomy is the primary treatment for colorectal polyps, crucial for preventing malignant degeneration into colorectal cancer (CRC).
    • Therapeutic challenges can limit the feasibility of endoscopic polypectomy for certain colorectal polyps.

    Purpose of the Study:

    • To identify challenging colorectal polyps.
    • To establish criteria for choosing between endoscopic and traditional surgery for polyp removal.

    Main Methods:

    • A retrospective analysis of 224 patients diagnosed with colorectal polyps between 2008-2011.
    • 222 patients underwent endoscopic polypectomy, with a focus on identifying difficult cases and surgical decision-making.

    Main Results:

    • Over a third (37.56%) of patients presented with difficult colorectal polyps.
    • Endoscopic polypectomy was successful in over 88% of cases; the remainder required conventional surgery.

    Conclusions:

    • Difficult polyps complicate endoscopic polypectomy, potentially increasing operative time and complication risks.
    • While criteria for difficult polyps are known, surgical approach selection often depends on surgeon preference, barring oncological indications for traditional surgery.