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GSTM1, GSTT1 and GSTP1 Genetic Variants in Multiple Urologic Cancers

D N Chirilă, R Popp, Ș Vesa

    Chirurgia (Bucharest, Romania : 1990)
    |July 10, 2015
    PubMed
    Summary

    Null genotypes in glutathione S-transferases (GSTs), specifically GSTM1 and GSTT1, are linked to increased risk for multiple urologic cancers and other cancer types. These genetic variations impact detoxification pathways, highlighting their role in cancer development.

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