Adverse pregnancy outcomes and cardiovascular risk factor management

Puja K Mehta1, Margo Minissian1, C Noel Bairey Merz2

  • 1Barbra Streisand Women's Heart Center, Cedars-Sinai Heart Institute, 127 S San Vicente Blvd, AHSP3600, Los Angeles, CA 90048.

Insights

Cardiovascular disease (CVD) is a major health risk for women. Adverse pregnancy outcomes, like pre-eclampsia, also increase future CVD risk, especially in minority and low-income women.

Area of Science:

  • Women's Health
  • Cardiovascular Disease Epidemiology
  • Preventive Cardiology

Background:

  • Cardiovascular disease (CVD) is the primary health concern for American women.
  • Established risk factors include hypertension, hyperlipidemia, diabetes, smoking, and obesity.
  • Adverse pregnancy outcomes (APOs) such as pre-eclampsia, eclampsia, and gestational diabetes are emerging risk factors for future CVD.

Purpose of the Study:

  • To highlight the link between adverse pregnancy outcomes and future cardiovascular disease (CVD) risk in women.
  • To emphasize the disproportionate CVD risk burden in women of low socioeconomic status and ethnic/racial minorities.
  • To advocate for early diagnosis and treatment of CVD risk factors in women, leveraging obstetrician/gynecologist visits.

Main Methods:

  • Review of current understanding of CVD risk factors in women.
  • Integration of adverse pregnancy outcomes as significant CVD risk indicators.
  • Proposal for embedding preventive care providers within OB/GYN settings.
  • Reference to American Heart Association (AHA)/American Stroke Association (ASA) guidelines for postpartum CVD risk assessment.

Main Results:

  • Adverse pregnancy outcomes are recognized as crucial indicators of future cardiovascular disease (CVD) risk.
  • Women of lower socioeconomic status and ethnic/racial minorities face a disproportionately higher CVD risk burden.
  • Obstetrician/gynecologist visits present a key opportunity for early CVD risk factor identification and intervention.

Conclusions:

  • The medical community must establish practical strategies for assessing and managing CVD risk factors in women.
  • Integrating preventive care within OB/GYN practices and establishing clear referral pathways are essential.
  • Postpartum evaluation for hypertension and other CVD risk factors is recommended for women with a history of pre-eclampsia, within 6 months to 1 year.

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