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Updated: Apr 7, 2026

In Vivo Real-Time Study of Drug Effects on Carotid Blood Flow in the Ovine Fetus
Published on: April 28, 2023
Propranolol during pregnancy for large chorioangioma
Patrick Padys1, Laurence Fouque2, Michel Le Duff2
1Department of Pediatrics CHU (University Hospital) and CIC 1414, Rennes, France.
Abstract:
Large chorioangiomas are frequently associated with adverse perinatal outcome. Its treatment remains invasive and controversial. Infantile hemangiomas which have numerous similarities with chorioangiomas are now usually treated with propranolol. This drug has been extensively used with a good tolerance during pregnancy in other indications. We report the first use of propranolol with the aim of limiting the increase in chorioangioma volume and avoiding the associated complications. The observed inhibition of the growth of the chorioangioma after introduction of propranolol argues for further evaluation of this treatment in this indication.
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