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Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
Published on: September 7, 2022
Insights
Fever in children can signal serious bacterial infections (SBI) in 7% of cases. Prompt identification of toxic signs and early treatment are crucial, especially for infants aged 1-3 months.
Area of Science:
- Pediatric infectious diseases
- Clinical microbiology
- Evidence-based medicine
Context:
- Fever is a common pediatric symptom, often viral.
- A significant percentage of children present with fever without an apparent source.
- Serious bacterial infections (SBI) can manifest initially as fever without source.
Purpose:
- To highlight the importance of identifying serious bacterial infections in febrile children.
- To emphasize the critical role of early toxic sign recognition in clinical examination.
- To outline specific management strategies for very young children (1-3 months) with fever without source.
Summary:
- Fever without source occurs in 7% of children and may indicate serious bacterial infections like pneumonia, meningitis, pyelonephritis, or bacteremia.
- Early identification of toxic signs during clinical examination is paramount for timely diagnosis.
- Infants aged 1-3 months with fever without source require specific management, including systematic investigations and empirical antibiotic therapy due to higher SBI prevalence.
Impact:
- Improved diagnostic accuracy for serious pediatric infections.
- Enhanced clinical decision-making for febrile infants.
- Reduced morbidity and mortality associated with untreated serious bacterial infections in children.
Abstract:
Fever in children is a very common symptom associated most of the time with a viral infection. However, in 7% of children, fever without source is the first symptom of a serious bacterial infection such as pneumonia, meningitis, pyelonephritis or bacteremia. The key point in clinical examination of these children is the early identification of toxic signs. Because SBI prevalence is higher in very young children (1-3 month-aged), they required a specific management with some systematic complementary investigations and a broad indication of probabilistic antibiotherapy treatment.
Related Concept Videos
Increased Body Temperature
Patterns of Fever
Types of Fever
Here are the different types of fever:
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Acute Pyelonephritis I: Introduction
