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Updated: Apr 7, 2026

Training Rats to Voluntarily Dive Underwater: Investigations of the Mammalian Diving Response
Published on: November 12, 2014
Delayed blood-brain barrier disruption after shallow-water diving demonstrated by magnetic resonance imaging
Amir Hadanny1, Sigal Tal2, Gregori Fishlev3
1Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, The Sagol Center for Hyperbaric Medicine and Research, Assaf Harofeh Medical Centre Zerifin 7030, Israel, Phone: +972-(0)544707381,
Abstract:
A 22-year-old diver presented to our emergency room complaining of headaches and left side numbness three days after diving to a depth of 6 metres for 25 minutes. On examination, he had left-sided hypaesthesia, and a post-contrast FLAIR brain MRI sequence revealed significant diffuse meningeal enhancement, indicating blood-brain-barrier (BBB) disruption. The patient was treated with hyperbaric oxygen; the initial four sessions resulted in only partial symptom improvement correlating with partial improvement in the MRI findings. Ten additional hyperbaric treatments resulted in complete resolution of the symptoms and normalization of MRI findings. The main aim of this case report is to present a probable, atypical, delayed-onset case of shallow-water decompression sickness culminating in significant BBB damage, which was demonstrated by special MRI techniques.

