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PERSISTENT CORNEAL EPITHELIAL DEFECT AFTER PARS PLANA VITRECTOMY.

Hsi-Fu Chen1, Ling Yeung, Ko-Jen Yang

  • 1*Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung, Taiwan; †University Eye Center, Taipei, Taiwan; and ‡Department of Chinese Medicine, Chang Gung University, Kwei-shan, Taoyuan, Taiwan.

Retina (Philadelphia, Pa.)
|July 14, 2015
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Summary
This summary is machine-generated.

Persistent corneal epithelial defects (PCED) after pars plana vitrectomy (PPV) occur in 4.8% of cases. Diabetes, perfluoropropane tamponade, and resident assistance are key risk factors, leading to poor visual outcomes.

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Area of Science:

  • Ophthalmology
  • Surgical Complications
  • Corneal Diseases

Background:

  • Pars plana vitrectomy (PPV) is a common ophthalmic surgery.
  • Corneal complications can arise post-PPV, impacting visual outcomes.
  • Persistent corneal epithelial defects (PCED) represent a significant challenge.

Purpose of the Study:

  • To determine the incidence of PCED following PPV.
  • To identify risk factors associated with PCED development.
  • To analyze the clinical course and visual outcomes of PCED.

Main Methods:

  • Retrospective chart review of 426 patients (511 eyes) undergoing PPV.
  • Definition of corneal complications and PCED (defect >2 weeks).
  • Comparison of demographic, surgical, and postoperative data between PCED and non-PCED groups.

Main Results:

  • Overall PCED incidence was 4.8%.
  • Diabetes mellitus, perfluoropropane tamponade, and first-year resident assistance were significant risk factors for PCED.
  • PCED eyes had significantly poorer final visual acuity compared to non-PCED eyes.
  • High incidence of herpes simplex virus keratitis in recalcitrant PCEDs.

Conclusions:

  • PCED is a notable complication of PPV with identifiable risk factors.
  • PCED is associated with poor visual prognosis.
  • Prompt and aggressive management of corneal defects post-PPV is crucial to prevent adverse outcomes.