Antibiotics for preventing recurrent sore throat.
Gareth J Y Ng1, Stephanie Tan, Anh N Vu
1Royal Brisbane & Women's Hospital, Butterfield drive, Herston, Brisbane, Queensland, Australia, Qld 4006.
The Cochrane Database of Systematic Reviews
|July 15, 2015
Summary
No studies support using antibiotics for recurrent sore throat. More research is needed to determine if antibiotics are effective and safe for preventing frequent sore throats.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Evidence-Based Medicine
Background:
- Recurrent sore throat is a common condition.
- Antibiotics are sometimes prescribed to prevent sore throat recurrence.
- Concerns exist regarding antibiotic resistance and effectiveness.
Purpose of the Study:
- To systematically review the evidence on antibiotic use for recurrent sore throat.
- To assess the effectiveness and safety of antibiotics in preventing sore throat recurrence.
Main Methods:
- A comprehensive search of multiple databases (CENTDG, CENTRAL, PubMed, EMBASE, CINAHL, Web of Science, ClinicalTrials.gov, ICTRP) was conducted.
- Inclusion criteria specified randomized controlled trials (RCTs) in adults and children with at least three sore throats per year.
- Studies required a follow-up of at least 12 months post-antibiotic therapy.
Main Results:
- No randomized controlled trials met the inclusion criteria for this review.
- A significant number of retrieved references were excluded after initial screening.
- Four studies were formally excluded after full-text review.
Conclusions:
- There is currently insufficient evidence to support the use of antibiotics for preventing recurrent sore throat.
- The potential adverse effects and costs of antibiotics should be considered.
- High-quality RCTs comparing antibiotics to placebo are needed to evaluate effectiveness, safety, and complications.
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