Epidemic Model with Isolation in Multilayer Networks

L G Alvarez Zuzek1, H E Stanley2, L A Braunstein3

  • 1Departamento de Física, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata, Instituto de Investigaciones Físicas de Mar del Plata (IFIMAR-CONICET), Deán Funes 3350, 7600 Mar del Plata, Argentina.

Scientific Reports
|July 16, 2015
PubMed

Insights

Implementing isolation in disease modeling significantly raises the epidemic threshold. The Susceptible-Infected-Isolated-Recovered (SIIR) model demonstrates that quarantining infected individuals effectively reduces disease spread, preventing epidemics.

Area of Science:

  • Epidemiology
  • Network Science
  • Mathematical Biology

Background:

  • The Susceptible-Infected-Recovered (SIR) model is widely used for airborne disease simulation.
  • Existing multilayer network models often neglect the crucial factor of infected individual isolation.
  • This oversight limits the accuracy of disease propagation predictions.

Purpose of the Study:

  • To introduce and analyze the Susceptible-Infected-Isolated-Recovered (SIIR) model in a two-layer network.
  • To quantify the impact of quarantining infected individuals on epidemic thresholds.
  • To investigate the influence of isolation duration and intensity on disease spread.

Main Methods:

  • Development of the SIIR model incorporating an isolation parameter (w) and isolation period (tw).
  • Application of link percolation theory to determine critical epidemic thresholds.
  • Simulation of the SIIR model to validate theoretical findings.

Main Results:

  • Isolation significantly increases the critical epidemic threshold, reducing disease transmissibility.
  • The threshold escalates with increased isolation parameter (w) and duration (tw).
  • A maximum isolation period exists, beyond which a critical 'w' can prevent epidemics entirely.

Conclusions:

  • Quarantining infected individuals is a highly effective strategy for controlling airborne disease spread in multilayer networks.
  • The SIIR model provides a more realistic framework for understanding epidemic dynamics than traditional SIR models.
  • Strategic implementation of isolation measures can prevent widespread outbreaks.

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