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Rumination in bipolar disorder: a systematic review
Érico de M Silveira1, Marcia Kauer-Sant'Anna1
1Laboratory of Molecular Psychiatry, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BR.
Rumination is a persistent symptom in bipolar disorder (BD) across all mood states, impacting cognitive functions. Further research into rumination as a transdiagnostic phenomenon in BD is warranted.
Area of Science:
- Psychiatry
- Clinical Psychology
- Neuroscience
Background:
- Rumination is a repetitive negative thinking pattern.
- Its role in bipolar disorder (BD) requires systematic investigation.
Purpose of the Study:
- To systematically review literature on rumination in bipolar disorder.
- To understand rumination's characteristics and implications in BD.
Main Methods:
- Systematic literature search of major databases (PubMed, PsycINFO, etc.).
- Inclusion criteria: studies on BD patients using validated rumination scales.
- Seventeen articles were analyzed from 105 initial references.
Main Results:
- Rumination occurs in all BD phases and is a stable interepisodic symptom.
- It correlates with depression, anxiety, and hypomania symptoms.
- Rumination can be triggered by both positive and negative affect.
Conclusions:
- Rumination appears independent of, yet closely related to, mood state in BD.
- It may negatively affect cognitive and executive functions, especially inhibitory control.
- Rumination is a key BD symptom and a potential target for Research Domain Criteria (RDoC) studies.
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