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Published on: August 16, 2021
Cardiac Amyloidosis Presenting With Cardiogenic Shock
Ashwad Afzal1, Sorin J Brener, Navneet Narula
11Department of Medicine, New York Methodist Hospital, Brooklyn, NY; 2Department of Pathology, Weill Cornell Medical Center, New York, NY; and 3Department of Cardiothoracic Surgery, New York Methodist Hospital, Brooklyn, NY.
Abstract:
Cardiac amyloidosis is an infiltrative disorder of the myocardium. It is the result of one of 4 types of amyloidosis: primary systemic (immunoglobulin light chain), secondary, familial (hereditary), or senile. Cardiac amyloidosis ultimately causes congestive heart failure due to irreversible restrictive cardiomyopathy. Because of the rapid progression of the disease, early recognition and determination of underlying etiology are important for tailored therapy. Current interventions range from conservative heart failure management to autologous stem cell and heart transplantation. We present a case of cardiac amyloidosis accompanying undiagnosed multiple myeloma to illustrate the rapid progression of the disease and the complexities of diagnosing and treating this disorder.
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