2015 Clinical trials update in sickle cell anemia

Natasha Archer1, Frédéric Galacteros2, Carlo Brugnara3

  • 1Pediatric Hematology/Oncology Dana-Farber/Children's Hospital Blood Disorders and Cancer Center, Boston, Massachusetts.

Summary

Sickle cell disease (SCD) involves HbS polymerization and red blood cell sickling. New therapies target these processes and associated inflammatory changes to prevent organ damage.

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