[Mechanisms of changes in the functional state of polymorphonuclear leukocytes in atherosclerosis]

Homeostasis of calcium was impaired in polymorphonuclear leukocytes of patients with atherosclerosis of cerebral vessels. Transformation of leukocyte membrane properties, related to Ca2+ permeability, was observed. At the same time, in some of these patients alterations of blood serum characteristics were found, which acquired an ability to sensitize the leukocyte Ca2+-transport system to the effect of activators.