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Typhoid Intestinal Perforations: Has the Clinical Importance Decreased in Eastern Anatolia for 36 Years?
S Selcuk Atamanalp1, Bunyami Ozogul1, Abdullah Kisaoglu1
1Department of General Surgery, Atatürk University Faculty of Medicine, Erzurum, Turkey.
The Eurasian Journal of Medicine
|July 17, 2015
Summary
Typhoid intestinal perforation (TIP) incidence decreased over 36 years in Eastern Anatolia, despite typhoid fever (TF) being endemic. Early recognition of TIP is crucial for improving patient outcomes in TF management.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Surgical Pathology
Background:
- Typhoid fever (TF) poses a significant health burden in developing nations.
- Typhoid intestinal perforation (TIP) is a severe complication of TF, necessitating surgical intervention.
Purpose of the Study:
- To assess the clinical significance and trends of TIP over a 36-year period in Eastern Anatolia.
- To analyze the epidemiological and surgical characteristics of TIP cases.
Main Methods:
- Retrospective review of clinical records for 84 surgically treated TIP cases.
- Analysis of TIP incidence, patient demographics, surgical procedures, and outcomes over 36 years.
Main Results:
- TIP incidence showed a decreasing trend over the 36-year study period.
- The majority of patients were male (78.6%) with a mean age of 37.1 years.
- High complication (84.5%) and mortality (10.7%) rates were observed, with resection and ileostomy being a common surgical approach.
Conclusions:
- Despite Eastern Anatolia being endemic for TF, a decline in TIP incidence was observed.
- Awareness and timely management of TIP can potentially improve the prognosis for patients with typhoid fever.
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