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Paediatric pancreatitis

John F Pohl1, Aliye Uc

  • 1aDepartment of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah School of Medicine, Salt Lake City, Utah bDepartment of Pediatric Gastroenterology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.

Current Opinion in Gastroenterology
|July 17, 2015
PubMed

Insights

Recent studies show paediatric pancreatitis incidence rivals adults, yet guidelines are lacking. Genetic factors and congenital issues are key risks for recurrent and chronic pancreatitis in children, demanding a unified research approach.

Area of Science:

  • Pediatric Gastroenterology
  • Pancreatology

Background:

  • Paediatric pancreatitis incidence is rising, approaching adult levels.
  • Lack of established diagnostic and treatment guidelines for children.
  • Significant socioeconomic burden associated with chronic pancreatitis in children.

Purpose of the Study:

  • To review recent advancements in paediatric pancreatitis.
  • To discuss the causes of paediatric pancreatitis.
  • To outline current management strategies for paediatric pancreatitis.

Main Methods:

  • Literature review of recent studies on paediatric pancreatitis.
  • Analysis of risk factors, including genetic and structural abnormalities.
  • Evaluation of current medical and surgical treatment options.

Main Results:

  • Genetic and congenital abnormalities are primary risk factors for recurrent and chronic pancreatitis in children.
  • Limited evidence supports the efficacy of current medical and surgical therapies for paediatric chronic pancreatitis.
  • Paediatric pancreatitis poses significant health challenges, with limited supporting data.

Conclusions:

  • Acute recurrent and chronic pancreatitis present major health concerns for children.
  • Existing therapies for paediatric pancreatitis lack robust supporting data due to small cohorts.
  • A multidisciplinary, multicentre approach is crucial for advancing understanding and treatment of paediatric pancreatic diseases.
Abstract

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