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FREQUENCY AND OUTCOME OF NECROTIZING ENTEROCOLITIS IN PRETERM NEONATES
Journal of Ayub Medical College, Abbottabad : JAMC
|July 18, 2015
Summary
Necrotizing enterocolitis (NEC) affects 14% of preterm neonates, a common gastrointestinal emergency. Outcomes reveal high mortality rates in this vulnerable population.
Area of Science:
- Neonatalogy
- Gastroenterology
- Pediatric Surgery
Background:
- Necrotizing enterocolitis (NEC) is a critical gastrointestinal emergency in neonates.
- NEC is associated with significant mortality and morbidity, particularly in premature infants.
- Understanding NEC frequency and outcomes in preterm infants is crucial for improving care.
Purpose of the Study:
- To determine the incidence of NEC in preterm neonates.
- To analyze the outcomes of preterm neonates diagnosed with NEC during hospitalization.
Main Methods:
- A descriptive case series was conducted in a Neonatal Intensive Care Unit (NICU).
- The study included all preterm neonates admitted to the NICU between August 2010 and February 2011.
- Data were collected using a pre-designed pro forma.
Main Results:
- A total of 196 neonates were enrolled; 28 (14%) were diagnosed with NEC.
- Among NEC patients, 16 (57.14%) were discharged, 11 (39.28%) expired, and 1 (3.5%) was referred.
- The findings indicate a substantial rate of NEC in the studied preterm population.
Conclusions:
- Preterm, low-birth-weight infants exhibit a high incidence of NEC in this setting.
- Mortality rates associated with NEC in preterm neonates remain alarmingly high.
- Further research and interventions are needed to reduce NEC-related morbidity and mortality.

