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Related Experiment Video

Updated: Apr 6, 2026

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
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Transanal total mesorectal excision--a systematic review.

Maya Xania Bjørn1, Sharaf Karim Perdawood

  • 1Guldbergsgade 80, 2200 Copenhagen N, Denmark. mxbjoern@gmail.com.

Danish Medical Journal
|July 18, 2015
PubMed
Summary

Transanal total mesorectal excision (TaTME) is a feasible surgical approach for rectal cancer. While preliminary results are encouraging, more long-term data are needed for comparison with standard TME procedures.

Area of Science:

  • Colorectal Surgery
  • Surgical Oncology
  • Minimally Invasive Surgery

Background:

  • Total mesorectal excision (TME) is the standard surgical treatment for mid and low rectal cancer.
  • Transanal TME (TaTME) is an emerging technique addressing challenges in pelvic dissection.
  • Existing surgical approaches include open, laparoscopic, and robotic methods.

Purpose of the Study:

  • To systematically evaluate the existing literature on the transanal total mesorectal excision (TaTME) procedure.
  • To assess the feasibility, preliminary outcomes, and complications associated with TaTME.
  • To identify areas requiring further research in TaTME.

Main Methods:

  • Systematic literature search conducted in PubMed and Embase databases.
  • Inclusion of all publications on TaTME, excluding review articles.

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  • Assessment of studies by both authors.
  • Main Results:

    • 29 studies comprising 336 patients were included, predominantly case reports and series.
    • Evidence quality is low, reflecting initial surgical experiences.
    • Preliminary results are encouraging for mid and low rectal tumors, particularly with bulky mesorectum.
    • Urethral injury is the most serious complication; oncological outcomes are acceptable with short follow-up.

    Conclusions:

    • Transanal TME (TaTME) is a feasible surgical option for mid and low rectal cancers.
    • Long-term data on functional results, recurrence, and survival are needed.
    • Further studies are required to compare TaTME with standard laparoscopic or robotic TME.