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Akihiro Araki1, Kiichiro Tsuchiya, Mamoru Watanabe

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Area of Science:

  • Gastroenterology
  • Medical Device Development
  • Endoscopy

Background:

  • The double-balloon endoscope (DBE) was introduced in Japan in September 2003.
  • Developed by Dr. Yamamoto, the DBE features balloons attached to a scope and an overtube.
  • Several variations of the DBE scope have been marketed for different applications.

Purpose of the Study:

  • To provide a detailed historical account of the development of balloon-assisted enteroscopy technologies.
  • To document the evolution from double-balloon to single-balloon systems for small intestinal examination.
  • To trace the timeline of these innovations from their inception in Japan to global availability.

Main Methods:

  • Review of the development and marketing history of specialized endoscopic devices.
  • Chronological documentation of the introduction of double-balloon and single-balloon endoscopes.
  • Analysis of the technological progression in small intestinal endoscopy.

Main Results:

  • The double-balloon endoscope (DBE) was first released in Japan in 2003.
  • Five distinct types of DBE scopes with varied functionalities were subsequently marketed.
  • A single-balloon small intestinal endoscope, a successor model, was launched in 2007.

Conclusions:

  • The evolution of balloon-assisted enteroscopy has significantly advanced small intestinal examination.
  • The development trajectory shows a progression towards specialized and potentially simpler endoscopic designs.
  • These innovations originated in Japan and have since seen international adoption.