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Updated: Apr 6, 2026

Multiplexing Focused Ultrasound Stimulation with Fluorescence Microscopy
Published on: January 7, 2019
A multi-frequency method for ultrasonic ranging
Ricardo Queirós1, Francisco Corrêa Alegria1, Pedro Silva Girão1
1Instituto de Telecomunicações/Instituto Superior Técnico, University of Lisbon, Portugal.
Abstract:
This paper presents a method for ultrasonic ranging based on the cross-correlation of two multi-frequency signals. The stimulus signal is composed by multiple sine-wave bursts/segments, each containing a different frequency and an integer number of periods. The frequency of each sine-wave burst is different from that of the adjacent bursts, but it is very close to the transducer resonant frequency. The time-of-flight (TOF) is estimated by finding the maximum of the cross-correlation. Interpolation is used to increase the measurement resolution. The experimental error corresponding to two standard deviations, for a range up to 1 m, is less than 0.3 mm.
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