Related Experiment Video
Updated: Apr 6, 2026

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing
Published on: December 23, 2022
Complete Genome Sequence of Corynebacterium pseudotuberculosis Strain 12C
Thiago Jesus Sousa1, Diego Mariano1, Doglas Parise1
1Laboratory of Cellular and Molecular Genetics, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
The complete genome sequence of Corynebacterium pseudotuberculosis strain 12C was determined. This bacterium was isolated from a sheep abscess in Brazil, providing insights into its genetic makeup.
Area of Science:
- Microbiology
- Genomics
Background:
- Corynebacterium pseudotuberculosis is an important animal pathogen.
- Understanding its genome is crucial for developing control strategies.
Purpose of the Study:
- To present the complete genome sequence of Corynebacterium pseudotuberculosis strain 12C.
- To provide a genomic resource for future research on this pathogen.
Main Methods:
- Whole-genome sequencing using the Ion Torrent Personal Genome Machine (PGM) platform.
- Fragment library preparation and sequencing with approximately 48-fold coverage.
Main Results:
- The genome is a circular chromosome of 2,337,451 base pairs.
- It contains 2,119 predicted coding sequences, 12 rRNAs, and 49 tRNAs.
- The G+C content of the genome is 52.83%.
Conclusions:
- The genome sequence of C. pseudotuberculosis strain 12C provides a valuable genetic blueprint.
- This data can aid in understanding virulence factors and developing diagnostic or therapeutic approaches.
More Related Videos
12:08Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies
Published on: August 20, 2021
08:34Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes
Published on: September 27, 2018
Related Concept Videos
Bacterial Phylum Actinobacteria
Bacterial Phylum Tenericutes
Diphtheria
Genomic DNA in Prokaryotes
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Bacterial Phylum Proteobacteria
Stringent Response in E. coli