Related Experiment Video
Updated: Apr 6, 2026
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
Prevalence of exclusive lower extremity metastases at (18)F-NaF PET/CT
Monique Beraldo Ordones1, Agnes Araujo Valadares2, Paulo Schiavom Duarte3
1MD, Resident, Center of Nuclear Medicine, Instituto de Radiologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (InRad/HCFMUSP), São Paulo, SP, Brazil.
Objective:
To evaluate the prevalence of exclusive lower extremity metastases, specifically in the femur and below the knee, observed at (18)F-NaF PET/CT.
Materials And Methods:
One thousand consecutive PET/CT studies were retrospectively evaluated for the presence of exclusive uptake in lower extremities suggesting metastatic involvement. The presumptive diagnoses based on such uptakes were subsequently obtained by evaluation of other imaging studies.
Results:
No exclusive uptake suggestive of metastasis below the femur was observed in the present series. Exclusive uptake was observed in the proximal femur with a presumptive diagnosis of metastasis in two patients.
Conclusion:
The prevalence of exclusive metastasis below the femur is low and scanning from head to knees is appropriate in most cases.
