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Related Experiment Videos

[Sudden deafness and Behçet's disease].

S Berrettini1, P Bruschini, S Sellari Franceschini

  • 1Clinique ORL, Université de Pisa.

Acta Oto-Rhino-Laryngologica Belgica
|January 1, 1989
PubMed
Summary
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Sudden deafness can occur during Behçet's disease flares. Early cortisone treatment led to full recovery of hearing and disease symptoms in observed patients with this rare audio-vestibular involvement.

Area of Science:

  • Otolaryngology
  • Rheumatology
  • Immunology

Background:

  • Behçet's disease is a rare multisystemic vasculitis.
  • It typically presents with oral ulcers, genital ulcers, and uveitis.
  • Audio-vestibular involvement is an increasingly recognized complication.

Observation:

  • Two patients with long-standing Behçet's disease experienced sudden sensorineural hearing loss during disease exacerbations.
  • Hearing loss was unilateral or bilateral in presentation.
  • One patient received prompt high-dose corticosteroid therapy.

Findings:

  • Both patients exhibited sensorineural hearing loss.
  • The patient treated with corticosteroids showed complete recovery of both audiovestibular function and general Behçet's disease symptoms.

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  • This suggests a potential link between disease activity and hearing impairment.

    • Implications:

    • Early diagnosis and intervention for audio-vestibular complications in Behçet's disease are crucial.
    • Corticosteroid therapy may be effective in managing sudden hearing loss associated with Behçet's disease flares.
    • Further research is warranted to understand the mechanisms of hearing loss in Behçet's disease.