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Implementation and Evaluation of a School-Based Human Papillomavirus Vaccination Program in Rural Kentucky.
Robin C Vanderpool1, Patrick J Breheny2, Peggy A Tiller3
1Department of Health Behavior, College of Public Health, University of Kentucky, Lexington, Kentucky.
American Journal of Preventive Medicine
|July 21, 2015
Summary
A school-based human papillomavirus (HPV) vaccination program in Kentucky improved HPV immunization rates among adolescents. The study demonstrated the effectiveness of school-based initiatives in increasing HPV vaccination initiation and completion for youth.
Area of Science:
- Public Health
- Adolescent Health
- Vaccinology
Background:
- Human papillomavirus (HPV) vaccination rates are low in the U.S., particularly in Kentucky, which has a high burden of HPV-related cancers.
- School-based immunization programs offer a promising strategy to increase HPV vaccination initiation and completion among adolescents.
Purpose of the Study:
- To design, implement, and evaluate a school-based HPV vaccination program in rural south-central Kentucky.
- To assess the feasibility and effectiveness of school-based HPV immunization in improving vaccination rates among youth.
Main Methods:
- An HPV vaccination program was implemented in two rural high schools during the 2012-2013 academic year.
- Data collection focused on parental consent form return rates, consent/declination, and HPV vaccination initiation and completion rates.
- Study guided by evidence-based immunization strategies and school nursing expertise.
Main Results:
- Out of 935 students, 511 returned consent forms (55% return rate).
- Of those with consent, 447 were HPV vaccine-naïve, with 315 (70%) initiating the vaccine series.
- 276 students (62%) completed the three-dose series, representing 45% of the total student body.
Conclusions:
- School-based HPV vaccination programs are an effective strategy for improving HPV vaccination rates in adolescents.
- Findings support the expansion of school-based immunization programs to address HPV-related cancer burden in Kentucky and nationwide.

