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[Systemic candidiasis in children with cancer]
J M Fernández Navarro1, A Verdeguer Miralles, J G Ruiz Soler
1Unidad de Oncología, Ciudad sanitaria La Fe Hospital Infantil, Valencia.
Anales Espanoles De Pediatria
|November 1, 1989
Summary
Systemic candidiasis, a common fungal infection in cancer patients, requires early and prolonged antifungal therapy for effective treatment, especially in cases of hepatosplenic candidiasis.
Area of Science:
- Medical Mycology
- Pediatric Oncology
- Infectious Diseases
Context:
- Systemic fungal infections are prevalent in terminally ill cancer patients.
- Systemic candidiasis incidence is rising.
- Eight pediatric cases of systemic candidiasis were analyzed between 1987-1988.
Purpose:
- To present cases of systemic candidiasis in children.
- To highlight the clinical presentations and outcomes.
- To emphasize the need for prompt and extended antifungal treatment.
Summary:
- Cases included fungal pneumonitis, hepatosplenic candidiasis, multisystemic involvement, and Candida sepsis.
- All patients presented with neutropenia and persistent fever unresponsive to antibiotics.
- Treatment duration and early intervention are critical for cure.
Impact:
- Underscores the importance of early diagnosis and aggressive antifungal treatment in pediatric systemic candidiasis.
- Informs clinical practice regarding the management of invasive fungal infections in immunocompromised children.
- Contributes to understanding the varied manifestations of candidiasis in pediatric oncology patients.