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Updated: Apr 6, 2026

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices
Published on: August 1, 2025
Transverse colonic varices successfully treated with endoscopic procedure
Takahiro Sato1, Katsu Yamazaki2, Jun Akaike2
1Department of Gastroenterology, Sapporo Kosei General Hospital, Kita 3 Higashi 8, Chuo-ku, Sapporo, 060-0033, Japan. taka.sato@ja-hokkaidoukouseiren.or.jp.
This study highlights endoscopic treatment for colonic varices in a patient with liver cirrhosis. Sclerotherapy and clipping effectively managed bleeding and reduced varix size.
Area of Science:
- Gastroenterology
- Hepatology
- Endoscopy
Background:
- Liver cirrhosis, often caused by hepatitis C virus (HCV) infection, can lead to portal hypertension.
- Portal hypertension increases the risk of developing varices in various locations, including the colon.
- Colonic varices are an uncommon but potentially serious complication of liver cirrhosis, leading to gastrointestinal bleeding.
Purpose of the Study:
- To report a case of colonic varices causing anal bleeding in a patient with liver cirrhosis.
- To describe the successful endoscopic management of colonic varices.
- To evaluate the long-term outcome of endoscopic treatment for colonic varices.
Main Methods:
- A 75-year-old female patient with HCV-positive liver cirrhosis presented with anal bleeding.
- Colonoscopy identified tortuous transverse colonic varices.
- Endoscopic injection sclerotherapy and endoscopic clipping were performed to treat the colonic varices.
Main Results:
- The endoscopic treatments successfully controlled the bleeding from colonic varices.
- Follow-up colonoscopy four months later showed ulcer scars and significant shrinkage of the varices.
- The patient experienced no further episodes of bleeding.
Conclusions:
- Endoscopic injection sclerotherapy and clipping are effective treatment options for colonic varices in patients with liver cirrhosis.
- These endoscopic interventions can lead to successful management of bleeding and long-term reduction in varix size.
- Colonic varices should be considered in the differential diagnosis of lower gastrointestinal bleeding in cirrhotic patients.
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