Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A fatty acid amide activates myeloid cells and improves neurovascular outcomes in retinal degeneration.

Nature neuroscience·2026

Same author

METLIN 960 K: An Empirical Tandem Mass Spectrometry Data Resource.

Analytical chemistry·2026

Same author

Untargeted Multiple Reaction Monitoring.

Analytical chemistry·2026

Same author

In-Source Fragmentation Annotation in Sterol Mass Spectrometry Imaging.

Analytical chemistry·2025

Same author

Adaptive Modeling of Tandem Mass Spectrometry Data: Creation of the METLIN 960K MRM Database.

Analytical chemistry·2025

Same author

Proceedings of the 15<sup>th</sup> International Newborn Brain Conference: Fetal and/or neonatal brain development, both normal and abnormal: Fota Island, Cork, Ireland, February 28<sup>th</sup> - March 2<sup>nd</sup> 2024.

Journal of neonatal-perinatal medicine·2025

Search research articles

Related Experiment Video

Updated: Apr 6, 2026

Author Spotlight: Advancing Metabolomics Analysis of Rare Hematopoietic Stem Cells

Author Spotlight: Advancing Metabolomics Analysis of Rare Hematopoietic Stem Cells

Published on: February 23, 2024

An Interactive Cluster Heat Map to Visualize and Explore Multidimensional Metabolomic Data.

Paul H Benton¹, Julijana Ivanisevic¹, Duane Rinehart¹

¹Scripps Center for Metabolomics, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, United States.

Metabolomics : Official Journal of the Metabolomic Society

|July 22, 2015

Summary

This summary is machine-generated.

XCMS Online introduces an interactive heat map for metabolomic data visualization. This tool overcomes limitations of traditional heat maps by integrating metabolite metadata and enabling deeper data exploration.

Keywords:

Anatomical brain regions Bioinformatics software Brain Metabolomics Interactive cluster heat map Metabolomics XCMS Online

More Related Videos

Author Spotlight: Separation of Coral Host Tissues and Algal Symbionts and Analyzing Their Metabolites

Author Spotlight: Separation of Coral Host Tissues and Algal Symbionts and Analyzing Their Metabolites

Published on: October 13, 2023

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Published on: October 2, 2016

Related Experiment Videos

Last Updated: Apr 6, 2026

Author Spotlight: Advancing Metabolomics Analysis of Rare Hematopoietic Stem Cells

Author Spotlight: Advancing Metabolomics Analysis of Rare Hematopoietic Stem Cells

Published on: February 23, 2024

Author Spotlight: Separation of Coral Host Tissues and Algal Symbionts and Analyzing Their Metabolites

Author Spotlight: Separation of Coral Host Tissues and Algal Symbionts and Analyzing Their Metabolites

Published on: October 13, 2023

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Published on: October 2, 2016

Area of Science:

Metabolomics
Bioinformatics
Data Visualization

Background:

Heat maps are standard for metabolomic data visualization, representing ion abundance with color.
Traditional heat maps struggle with large datasets, lacking details on m/z and retention time.
XCMS Online is a cloud-based platform for processing, analyzing, and visualizing metabolomic data.

Purpose of the Study:

To introduce an interactive cluster heat map within XCMS Online.
To address limitations of traditional heat maps in displaying large metabolomic datasets.
To enhance metabolite data exploration by integrating key parameters and databases.

Main Methods:

Development of an interactive heat map feature in XCMS Online software.
Integration of clickable elements for zooming and exploring metabolite metadata.
Linking interactive heat map features to METLIN metabolite database and other visualizations (EICs, Box-and-whisker plots, mass spectra).

Main Results:

The interactive heat map allows users to explore specific metabolite metadata.
Users can zoom into regions of interest within the heat map.
The tool successfully visualizes and aids in the analysis of metabolomic data from mouse brain regions.

Conclusions:

The interactive heat map in XCMS Online enhances metabolomic data visualization and analysis.
This tool provides a more informative and interactive approach compared to traditional heat maps.
It facilitates deeper insights into complex metabolomic datasets by linking visualization with detailed metadata.