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Updated: Apr 6, 2026
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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
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Contrast Medium-Induced Acute Kidney Injury
Umar Sadat1, Ammara Usman2, Jonathan R Boyle1
1Cambridge Vascular Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Cardiorenal Medicine
|July 22, 2015
Summary
Contrast medium-induced acute kidney injury (CI-AKI) is a common cause of hospital-acquired renal insufficiency. Understanding CI-AKI
Area of Science:
- Nephrology
- Radiology
- Pharmacology
Background:
- Contrast medium-induced acute kidney injury (CI-AKI) is a significant cause of hospital-acquired renal insufficiency.
- The incidence of CI-AKI is rising due to increased contrast-enhanced radiological procedures and an aging population.
- Effective strategies for CI-AKI prevention and treatment are crucial.
Purpose of the Study:
- To provide high-yield information on the aetiology, diagnosis, and management of CI-AKI.
- To review current understanding based on robust scientific evidence.
- To inform the development of novel diagnostic and therapeutic approaches.
Main Methods:
- Review of randomized controlled trials (RCTs).
- Analysis of meta-analyses and systematic reviews.
- Consultation of international consensus guidelines.
Main Results:
- CI-AKI is a major concern in healthcare settings.
- Evidence synthesis from high-level studies informs current practices.
- Focus on etiology, diagnostics, prophylaxis, and therapeutics.
Conclusions:
- Further research and clinical attention are needed for CI-AKI.
- Evidence-based strategies are essential for reducing CI-AKI incidence and impact.
- Improved understanding can lead to better patient outcomes.
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