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Updated: Apr 6, 2026

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
Published on: September 11, 2013
RECURRENT SUBRETINAL HEMORRHAGE ASSOCIATED WITH RIVAROXABAN ANTICOAGULATION
Michelle R Boyce1, Bradley E Barth, Ajay Singh
1Departments of *Ophthalmology, and †Emergency Medicine, University of Kansas School of Medicine, Kansas City, Kansas.
Purpose:
To report a case of spontaneous recurrent significant subretinal hemorrhage in a patient on rivaroxaban (Xarelto).
Methods:
A case report of a 63-year-old man on rivaroxaban with peripapillary choroidal neovascular membrane and macula involving subretinal hemorrhage.
Results:
Improvement in visual acuity from 20/200 to 20/30 and restoration of foveal contour after pneumatic displacement of hemorrhage with C3F8 gas and subsequent treatment with ranibizumab.
Conclusion:
The authors report a case of recurrent subretinal hemorrhage associated with rivaroxaban use. Pneumatic displacement and subsequent treatment of choroidal neovascular membrane with intravitreal ranibizumab improved visual acuity.
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