Related Experiment Video For (170.1790) Confocal microscopy
Updated: Apr 6, 2026

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
Published on: May 11, 2014
Confocal foveated endomicroscope for the detection of esophageal carcinoma
Adam Shadfan1, Anne Hellebust1, Rebecca Richards-Kortum1
1Rice University, Bioengineering Department, 6100 Main Street, Houston, TX 77005-1892, USA.
Abstract:
By mimicking the variable resolution of the human eye, a newly designed foveated endomicroscopic objective shows the potential to improve current endoscopic based techniques of identifying abnormal tissue in the esophagus and colon. The prototype miniature foveated objective is imaged with a confocal microscope to provide large field of view images combined with a high resolution central region to rapidly observe morphological structures associated with cancer development in a mouse model.
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