Related Experiment Video
Updated: Apr 6, 2026
Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
Published on: January 9, 2019
Imaging for Staging and Response Assessment in Lymphoma
Sarah A Johnson1, Anita Kumar1, Matthew J Matasar1
1From the Department of Radiology (S.A.J., J.R.), Department of Medicine (A.K., M.J.M.), and Molecular Imaging and Therapy Service, Department of Radiology (H.S.), Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065.
This review details updated imaging criteria for lymphoma staging and treatment response assessment. It familiarizes radiologists with the Lugano classification for computed tomography (CT) and positron emission tomography (PET)/CT scans.
Area of Science:
- Oncology
- Radiology
- Medical Imaging
Background:
- Lymphoma is a complex disease with ongoing advancements in diagnosis and treatment.
- Diagnostic imaging is crucial for staging and assessing treatment response in lymphoma patients.
- Evolving staging systems and response evaluation criteria, including CT and PET/CT, are vital for clinical decision-making.
Purpose of the Study:
- To provide an overview of updated computed tomography (CT) and fluorine-18 fluorodeoxyglucose positron emission tomography (PET)/CT response criteria for lymphoma.
- To familiarize radiologists with the clinically relevant aspects of lymphoma imaging, focusing on the Lugano classification.
- To offer a concise clinical update on lymphoma and its associated imaging findings.
Main Methods:
- Review of updated staging and response assessment criteria for lymphoma.
- Focus on the Lugano classification for both Hodgkin and non-Hodgkin lymphoma.
- Integration of computed tomography (CT) and positron emission tomography (PET)/CT imaging modalities.
Main Results:
- The Lugano classification represents the most recent standardized system for lymphoma staging and response assessment.
- Updated CT and PET/CT criteria are essential for accurate treatment decisions and research direction.
- Standardized criteria improve consistency in evaluating lymphoma progression and treatment efficacy.
Conclusions:
- Standardized imaging criteria, particularly the Lugano classification, are fundamental for effective lymphoma management.
- Familiarity with updated CT and PET/CT response criteria enhances radiologists' ability to interpret lymphoma imaging accurately.
- This review equips healthcare professionals with essential knowledge for lymphoma diagnosis, staging, and response assessment.
