Functional Renal Assessment via Dynamic LAFOV ¹⁸F-FDG PET/CT in a Patient with Recurrent Extranodal Marginal-Zone...

Area of Science:

• Oncologic Imaging
• Nuclear Medicine
• Renal Physiology

Background:

• Extranodal marginal zone B-cell lymphoma can recur, requiring vigilant monitoring.
• Standard oncologic imaging primarily focuses on anatomical assessment of disease.
• Functional imaging offers complementary information beyond anatomical structure.

Purpose of the Study:

• To report a case of recurrent extranodal marginal zone B-cell lymphoma.
• To evaluate the utility of dynamic long-axial-field-of-view 18F-FDG PET/CT in assessing renal function incidentally.
• To highlight the potential of advanced PET/CT techniques in comprehensive patient assessment.

Main Methods:

• A 72-year-old male patient with recurrent extranodal marginal zone B-cell lymphoma underwent dynamic long-axial-field-of-view 18F-FDG PET/CT.
• Analysis of the dynamic acquisition included review of maximum-intensity-projection cine.
• Standard anatomical imaging was compared with functional data derived from PET/CT.

Main Results:

• The dynamic 18F-FDG PET/CT successfully detected extensive recurrent lymphoma.
• Incidental findings revealed delayed uptake and excretion in the left kidney, indicating impaired renal function.
• The functional renal assessment influenced the patient's treatment management.

Conclusions:

• Dynamic long-axial-field-of-view 18F-FDG PET/CT can provide incidental renal functional information during oncologic imaging.
• This advanced imaging modality offers a dual benefit of disease detection and functional assessment.
• The findings suggest a potential role for dynamic PET/CT in comprehensive patient evaluation and management.