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Long non-coding RNAs: biomarkers for acute leukaemia subtypes

Carolina P de Souza Melo1, Catharina B Campos1, Juliana de Oliveira Rodrigues2

  • 1Laboratório BIOCOD Biotecnologia Ltda, Vespasiano, Brazil.

British Journal of Haematology
|July 25, 2015
PubMed
Summary

No abstract available in PubMed .

Keywords:
biomarkerclassification modelgene expression profileleukaemialncRNA

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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